Hot Articles Directory Indiana: 2016

Thursday, September 29, 2016

Clipto

Clipto may be available in the countries listed below.

Ingredient matches for Clipto

Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Clipto in the following countries:

Spain

International Drug Name Search

Porabutin

Porabutin may be available in the countries listed below.

Ingredient matches for Porabutin

Oxybutynin

Oxybutynin hydrochloride (a derivative of Oxybutynin) is reported as an ingredient of Porabutin in the following countries:

Japan

International Drug Name Search

Lanicor

Lanicor may be available in the countries listed below.

Ingredient matches for Lanicor

Digoxin

Digoxin is reported as an ingredient of Lanicor in the following countries:

Argentina

Botswana

Croatia (Hrvatska)

Czech Republic

Ecuador

Germany

Ghana

Kenya

Luxembourg

Malawi

Namibia

Nigeria

Sudan

Tanzania

Uganda

Venezuela

Zambia

Zimbabwe

International Drug Name Search

Lanoxin Elixir

Pronunciation: di-JOX-in
Generic Name: Digoxin
Brand Name: Lanoxin

Lanoxin Elixir is used for:

Treating heart failure or slowing the heart rate in patients with chronic atrial fibrillation, a type of abnormal heart rhythm. It may also be used for other conditions as determined by your doctor.

Lanoxin Elixir is a digitalis glycoside. It works by increasing the force of contraction of the heart and slowing heart rate.

Do NOT use Lanoxin Elixir if:

you are allergic to any ingredient in Lanoxin Elixir

you are taking sucralfate

you have certain types of heart rhythm problems, such as ventricular fibrillation

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lanoxin Elixir:

Some medical conditions may interact with Lanoxin Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have severe heart failure or other heart problems (eg, inflammation, heart block, cor pulmonale, cardiomyopathy, amyloid heart disease ), extra heart beats (premature ventricular contractions [PVCs]), other types of abnormal heart rhythm, heart problems due to low thiamine (eg, beriberi heart disease), Wolff-Parkinson-White syndrome, heart blood vessel problems, or fainting due to a heart problem

if you have severe kidney, liver, or lung problems, or thyroid problems

if you have low blood levels of calcium, magnesium, or potassium, or high blood levels of potassium or calcium

if you have had a recent heart attack

Some MEDICINES MAY INTERACT with Lanoxin Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

Alprazolam, amiodarone, amphotericin B, anticholinergics (eg, propantheline), beta-blockers (eg, propranolol, carvedilol), bupivacaine, calcium, cyclosporine, diltiazem, diphenoxylate, diuretics (eg, furosemide, hydrochlorothiazide), indomethacin, itraconazole, macrolides (eg, erythromycin), propafenone, quinidine, quinine, spironolactone, stimulants (eg, amphetamine), succinylcholine, sympathomimetics (eg, albuterol, pseudoephedrine), tetracyclines (eg, doxycycline), thioamines (eg, methimazole), or verapamil because they may increase the risk of Lanoxin Elixir's side effects, especially on the heart

Acarbose, certain anticancer medicines, cholestyramine, colestipol, kaolin-pectin, metoclopramide, penicillamine, rifampin, sulfasalazine, or thyroid hormones (eg, levothyroxine) because they may decrease Lanoxin Elixir's effectiveness

Oral aminoglycosides (eg, neomycin) because the actions and side effects of Lanoxin Elixir may be increased or decreased

Spironolactone because it may interfere with certain lab tests for digoxin blood levels and give incorrect readings

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lanoxin Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lanoxin Elixir:

Use Lanoxin Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Lanoxin Elixir by mouth. Do not take it within 1 hour of food high in fiber.

Do not take antacids containing aluminum or magnesium, cholestyramine, or colestipol within 2 to 4 hours of taking Lanoxin Elixir.

Use the dropper that comes with Lanoxin Elixir to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

If you miss a dose of Lanoxin Elixir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lanoxin Elixir.

Important safety information:

Lanoxin Elixir may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Lanoxin Elixir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Tell your doctor or dentist that you take Lanoxin Elixir before you receive any medical or dental care, emergency care, or surgery.

Lanoxin Elixir may interfere with certain lab tests, including an electrocardiogram (ECG). Be sure your doctor and lab personnel know you are using Lanoxin Elixir.

Lab tests, including ECG, electrolytes, kidney function, and blood digoxin levels, may be performed while you use Lanoxin Elixir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Lanoxin Elixir with caution in the ELDERLY; they may be more sensitive to its effects.

Use Lanoxin Elixir with extreme caution in NEWBORN INFANTS, especially those who are premature or immature; they may be more sensitive to its effects.

Poisoning may occur in children who accidently swallow Lanoxin Elixir or receive too much medicine. In case of an overdose, call a doctor or poison control center right away.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lanoxin Elixir while you are pregnant. Lanoxin Elixir is found in breast milk. If you are or will be breast-feeding while you are taking Lanoxin Elixir, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lanoxin Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, yellow vision, or other vision changes; confusion; fast, slow, or irregular heartbeat; hallucinations; mood or mental changes (eg, depression); severe or persistent nausea, vomiting, or stomach pain; unusual bruising or bleeding; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lanoxin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include very fast, very slow, or irregular heartbeat.

Proper storage of Lanoxin Elixir:

Store Lanoxin Elixir at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lanoxin Elixir out of the reach of children and away from pets.

General information:

If you have any questions about Lanoxin Elixir, please talk with your doctor, pharmacist, or other health care provider.

Lanoxin Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lanoxin Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Lanoxin resources

Lanoxin Side Effects (in more detail)
Lanoxin Use in Pregnancy & Breastfeeding
Drug Images
Lanoxin Drug Interactions
Lanoxin Support Group
0 Reviews for Lanoxin - Add your own review/rating

Compare Lanoxin with other medications

Atrial Fibrillation
Heart Failure

Wednesday, September 28, 2016

Prefaxine

Prefaxine may be available in the countries listed below.

Ingredient matches for Prefaxine

Venlafaxine

Venlafaxine hydrochloride (a derivative of Venlafaxine) is reported as an ingredient of Prefaxine in the following countries:

Slovakia

International Drug Name Search

Clonazone

Clonazone may be available in the countries listed below.

Ingredient matches for Clonazone

Tosylchloramide Sodium

Tosylchloramide Sodium is reported as an ingredient of Clonazone in the following countries:

Belgium

International Drug Name Search

Pulmicort Nasal Turbuhaler

Pulmicort Nasal Turbuhaler may be available in the countries listed below.

Ingredient matches for Pulmicort Nasal Turbuhaler

Budesonide

Budesonide is reported as an ingredient of Pulmicort Nasal Turbuhaler in the following countries:

Chile

International Drug Name Search

Saphris

Generic Name: asenapine (Sublingual route)

a-SEN-a-peen

Sublingual route(Tablet)

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Asenapine is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

Saphris

Available Dosage Forms:

Tablet

Uses For Saphris

Asenapine is used to treat symptoms of psychotic (mental) disorders, such as schizophrenia, mania, or bipolar disorder. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.

Before Using Saphris

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of asenapine in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of asenapine in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Cisapride

Dronedarone

Mesoridazine

Metoclopramide

Pimozide

Sparfloxacin

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acecainide

Ajmaline

Alfuzosin

Amiodarone

Amisulpride

Amitriptyline

Amoxapine

Apomorphine

Arsenic Trioxide

Astemizole

Azimilide

Azithromycin

Bretylium

Chloroquine

Chlorpromazine

Ciprofloxacin

Citalopram

Clarithromycin

Clomipramine

Clozapine

Crizotinib

Dasatinib

Desipramine

Disopyramide

Dofetilide

Dolasetron

Droperidol

Erythromycin

Flecainide

Fluconazole

Gatifloxacin

Gemifloxacin

Granisetron

Halofantrine

Haloperidol

Hydroquinidine

Ibutilide

Iloperidone

Imipramine

Lapatinib

Levofloxacin

Lopinavir

Lumefantrine

Mefloquine

Methadone

Moxifloxacin

Nilotinib

Norfloxacin

Nortriptyline

Octreotide

Ofloxacin

Ondansetron

Paliperidone

Pazopanib

Perflutren Lipid Microsphere

Pirmenol

Posaconazole

Prajmaline

Procainamide

Prochlorperazine

Promethazine

Propafenone

Protriptyline

Quetiapine

Quinidine

Quinine

Ranolazine

Risperidone

Salmeterol

Saquinavir

Sematilide

Sertindole

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Sultopride

Sunitinib

Tedisamil

Telavancin

Telithromycin

Terfenadine

Tetrabenazine

Thioridazine

Toremifene

Trazodone

Trifluoperazine

Trimipramine

Vandetanib

Vardenafil

Vemurafenib

Voriconazole

Ziprasidone

Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Fluvoxamine

Paroxetine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of Saphris

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

To use the sublingual tablet:

Make sure your hands are dry before you handle the tablet.

Do not open the blister pack that contains the tablet until you are ready to take it.

Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil.

Place the tablet under your tongue. It should melt quickly.

Do not crush, chew, or swallow the tablet.

Do not eat or drink anything for at least 10 minutes after using this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (sublingual tablets):
- For bipolar disorder:
  - Adults—At first, 10 milligrams (mg) two times a day. Your doctor may adjust your dose as needed.
  - Children—Use and dose must be determined by your doctor.
- For schizophrenia:
  - Adults—At first, 5 milligrams (mg) two times a day. Your doctor may increase your dose as needed.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Saphris

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.

Stop using this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while using this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

For diabetic patients: This medicine may affect your blood sugar levels. Check with your doctor right away if you have increased thirst or increased urination. If you notice a change in the results of your urine or blood sugar tests, or if you have any questions, check with your doctor.

This medicine may increase your weight. Your doctor may need to check your weight on a regular basis while you are using this medicine. Talk to your doctor about ways to prevent weight gain.

This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; dizziness or lightheadedness; trouble breathing; trouble swallowing; or any swelling of your hands, face, tongue, or throat while you are using this medicine.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position suddenly. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

Asenapine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

This medicine can cause changes in the heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects. Contact your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.

This medicine may cause dizziness, drowsiness, trouble with thinking, or trouble with controlling body movements. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that requires you to be alert, well-coordinated, or able to think well.

This medicine might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might vomit or have an upset stomach. Do not get too hot while you are exercising. Avoid places that are very hot. Call your doctor if you are too hot and cannot cool down.

Asenapine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies. If you or your caregiver notice any of these side effects, tell your doctor right away.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicines including other narcotics; medicine for seizures (e.g., barbiturates); muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Saphris Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abnormal or decreased touch sensation

inability to move the eyes

inability to sit still

increase in body movements

increased blinking or spasms of the eyelid

lip smacking or puckering

need to keep moving

puffing of the cheeks

rapid or worm-like movements of the tongue

restlessness

shakiness in the legs, arms, hands, or feet

sticking out of tongue

trembling or shaking of the hands or feet

trouble with breathing, speaking, or swallowing

twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

uncontrolled chewing movements

uncontrolled twisting movements of the neck, trunk, arms, or legs

unusual facial expressions

weakness of the arms and legs

Less common

Blurred vision

dizziness

headache

nervousness

pounding in the ears

slow or fast heartbeat

Rare

Black, tarry stools

bleeding gums

blood in the urine or stools

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

changes in patterns and rhythms of speech

coma

confusion

convulsions

decreased urine output

fast, pounding, or irregular heartbeat or pulse

increased thirst

muscle pain or cramps

nausea or vomiting

pale skin

pinpoint red spots on the skin

shortness of breath

slurred speech

swelling of the face, ankles, or hands

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

sleepiness or unusual drowsiness

sleeplessness

trouble sleeping

unable to sleep

unusually deep sleep

unusually long duration of sleep

Less common

Acid or sour stomach

belching

depression

difficulty with moving

dry mouth

fear or nervousness

heartburn

increased appetite

increased watering of the mouth

increased weight

indigestion

irritability

muscle pain or stiffness

pain in the arms or legs

pain in the joints

stomach discomfort, upset, or pain

toothache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Saphris side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More Saphris resources

Saphris Side Effects (in more detail)
Saphris Use in Pregnancy & Breastfeeding
Drug Images
Saphris Drug Interactions
Saphris Support Group
84 Reviews for Saphris - Add your own review/rating

Saphris Prescribing Information (FDA)

Saphris Consumer Overview

Saphris Monograph (AHFS DI)

Saphris MedFacts Consumer Leaflet (Wolters Kluwer)

Asenapine Professional Patient Advice (Wolters Kluwer)

Compare Saphris with other medications

Bipolar Disorder
Post Traumatic Stress Disorder
Schizoaffective Disorder
Schizophrenia

Iso-Eremfat

Iso-Eremfat may be available in the countries listed below.

Ingredient matches for Iso-Eremfat

Isoniazid

Isoniazid is reported as an ingredient of Iso-Eremfat in the following countries:

Georgia

Germany

Rifampicin

Rifampicin is reported as an ingredient of Iso-Eremfat in the following countries:

Georgia

Germany

International Drug Name Search

Pramipex

Pramipex may be available in the countries listed below.

Ingredient matches for Pramipex

Pramipexole

Pramipexole is reported as an ingredient of Pramipex in the following countries:

India

International Drug Name Search

Impugan

Impugan may be available in the countries listed below.

Ingredient matches for Impugan

Furosemide

Furosemide is reported as an ingredient of Impugan in the following countries:

Bahrain

Cyprus

Egypt

Ethiopia

Indonesia

Iraq

Jordan

Kuwait

Lebanon

Libya

Qatar

Saudi Arabia

Sudan

Sweden

United Arab Emirates

Yemen

International Drug Name Search

Lodosyn

Pronunciation: KAR-bi-DOE-pa
Generic Name: Carbidopa
Brand Name: Lodosyn

Lodosyn is used for:

Treating symptoms associated with Parkinson disease and parkinsonism-like symptoms caused by other conditions. It is used in combination with another medicine called levodopa. It may also be used for other conditions as determined by your doctor.

Lodosyn is an antiparkinson agent. It works by helping levodopa to reach the brain.

Do NOT use Lodosyn if:

you are allergic to any ingredient in Lodosyn

you have narrow-angle glaucoma, undiagnosed skin growths, skin cancer, or a history of skin cancer

you have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lodosyn:

Some medical conditions may interact with Lodosyn. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have an irregular heartbeat, heart disease, ulcer, seizures, blood pressure problems, asthma, lung problems, liver or kidney problems, blood or hormone problems, stomach or intestinal bleeding, glaucoma, or a history of heart attack, mental or mood problems, or suicidal thoughts or attempts

Some MEDICINES MAY INTERACT with Lodosyn. Tell your health care provider if you are taking any other medicines, especially any of the following:

MAOIs (eg, phenelzine) because the risk of severe high blood pressure may be increased

Tricyclic antidepressants (eg, amitriptyline) because the risk of high blood pressure or unusual muscle movements may be increased

Metoclopramide because side effects may occur

Blood pressure medicines or selegiline because the risk of severe dizziness on standing may be increased

Butyrophenones, (eg, haloperidol), isoniazid, papaverine, phenothiazines (eg, chlorpromazine), or risperidone because they may decrease Lodosyn's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lodosyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lodosyn:

Use Lodosyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Lodosyn by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Carefully follow the dosing schedule given to you by your health care provider. It may take several weeks to a few months to notice benefit from use because the dose is carefully adjusted over time.

If you are also taking iron salts (eg, ferrous sulfate), do not take them within 2 hours before or 2 hours after taking Lodosyn. Check with your doctor if you have questions

Take Lodosyn on a regular schedule to get the most benefit from it. Taking Lodosyn at the same times each day will help you to remember to take it.

Continue to take Lodosyn even if you feel well. Do not miss any doses.

If you have been taking levodopa, do not start taking Lodosyn until at least 12 hours after your final dose of levodopa.

If you miss a dose of Lodosyn, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lodosyn.

Important safety information:

Lodosyn may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Lodosyn with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Lodosyn; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

Lodosyn may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Tell your doctor or dentist that you take Lodosyn before you receive any medical or dental care, emergency care, or surgery.

Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Lodosyn. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.

Diabetes patients - Lodosyn may cause the results of some tests for urine glucose or urine ketones to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Do not suddenly stop taking Lodosyn. Some conditions may become worse when Lodosyn is suddenly stopped. Your dose may need to be slowly lowered by your doctor to avoid side effects.

Gradually increase physical activity as your symptoms improve.

A dark color (red, brown, or black) may appear in your saliva, urine, or sweat after taking Lodosyn. This is not harmful.

The effects of Lodosyn might start to wear off between doses. Talk with your doctor if Lodosyn stops working well or if your condition worsens.

Lodosyn may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Lodosyn

Lab tests, including complete blood cell counts and liver function tests, may be performed while you use Lodosyn. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Lodosyn with caution in ELDERLY patients; they may be more sensitive to its effects.

Lodosyn should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lodosyn while you are pregnant. It is not known if Lodosyn is found in breast milk. If you are or will be breast-feeding while you use Lodosyn, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lodosyn:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Confusion; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; taste changes; trouble sleeping; upset stomach; urinary tract infection; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in vomit; chest pain; confusion; depression; fast or irregular heartbeat; fever; hallucinations; increased sweating; mental or mood changes; muscle pain or unusual stiffness; severe abdominal pain; severe lightheadedness or fainting; sore throat; thoughts of suicide; unusual bruising or bleeding; unusual or painful movements or spasms of the face, eyelids, mouth, tongue, arms, hands, or legs; vision changes (blurred/double vision); yellowing of the skin or eyes.

See also: Lodosyn side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lodosyn:

Store Lodosyn at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lodosyn out of the reach of children and away from pets.

General information:

If you have any questions about Lodosyn, please talk with your doctor, pharmacist, or other health care provider.

Lodosyn is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lodosyn. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Lodosyn resources

Lodosyn Side Effects (in more detail)
Lodosyn Use in Pregnancy & Breastfeeding
Drug Images
Lodosyn Drug Interactions
Lodosyn Support Group
0 Reviews for Lodosyn - Add your own review/rating

Lodosyn Prescribing Information (FDA)

Lodosyn Concise Consumer Information (Cerner Multum)

Lodosyn Monograph (AHFS DI)

Carbidopa Professional Patient Advice (Wolters Kluwer)

Compare Lodosyn with other medications

GTP-CH Deficiency
Neuroleptic Malignant Syndrome
Parkinsonian Tremor

Calcio-cit simple

Calcio-cit simple may be available in the countries listed below.

Ingredient matches for Calcio-cit simple

Calcium Citrate

Calcium Citrate is reported as an ingredient of Calcio-cit simple in the following countries:

Argentina

International Drug Name Search

Loxitane

Generic Name: loxapine (Oral route)

LOX-a-peen

Oral route(Capsule)

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared with placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Loxapine is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

Loxitane

Available Dosage Forms:

Tablet

Capsule

Solution

Therapeutic Class: Antipsychotic

Chemical Class: Dibenzoxazepine

Uses For Loxitane

Loxapine is used to treat a mental condition called schizophrenia.

This medicine is available only with your doctor's prescription.

Before Using Loxitane

Allergies

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of loxapine in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of loxapine in geriatric patients. However, elderly patients (especially females) are more likely to have tardive dyskinesia (a movement disorder), which may require caution in patients receiving loxapine.

Breast Feeding

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Metoclopramide

Hydromorphone

Lithium

Milnacipran

Tramadol

Zotepine

Betel Nut

Carbamazepine

Interactions with Food/Tobacco/Alcohol

Proper Use of Loxitane

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Dosing

For schizophrenia:
- For oral dosage form (capsules):
  - Adults—At first, 20 to 50 milligrams (mg) per day, divided and given in two to four doses per day. Your doctor may increase your dose if needed. However, the dose is usually not more than 250 mg per day.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Loxitane

It is very important that your doctor check your progress at regular visits, especially during the first few months of treatment with this medicine. This will allow changes in your dose and to check for unwanted effects.

Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely. This will allow your body time to adjust and to keep your condition from becoming worse.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever or allergies; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while taking this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

Stop taking this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine may cause some people to become drowsy or less alert than they are normally, especially when the amount of medicine is increased. Even if you take this medicine at bedtime, you may feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Although it is not a problem for most patients, dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. However, if the problem continues or gets worse, check with your doctor.

Loxapine may cause dry mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Loxitane Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Difficulty with speaking or swallowing

lip smacking or puckering

loss of balance control

mask-like face

puffing of the cheeks

rapid or fine, worm-like movements of the tongue

restlessness or desire to keep moving

shuffling walk

slowed movements

stiffness of the arms and legs

trembling and shaking of the fingers and hands

uncontrolled chewing movements

uncontrolled movements of the arms or legs

Less common

Constipation (severe)

difficult urination

inability to move the eyes

muscle spasms, especially of the neck and back

skin rash

twisting movements of the body

Rare

Convulsions (seizures)

difficult or fast breathing

fast heartbeat or irregular pulse

fever (high)

high or low blood pressure

increased blinking or spasms of the eyelid

increased sweating

loss of bladder control

muscle stiffness (severe)

sore throat and fever

uncontrolled twisting movements of neck, trunk, arms, or legs

unusual bleeding or bruising

unusual facial expressions or body positions

unusual tiredness or weakness

unusually pale skin

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Dizziness (severe)

drowsiness (severe)

muscle trembling, jerking, stiffness, or uncontrolled movements (severe)

troubled breathing (severe)

unusual tiredness or weakness (severe)

More common

Blurred vision

confusion

dizziness, lightheadedness, or fainting

drowsiness

dryness of the mouth

Less common

Constipation (mild)

decreased sexual ability

enlargement of breasts (males and females)

headache

increased sensitivity of the skin to sun

missing menstrual periods

nausea or vomiting

trouble with sleeping

unusual secretion of milk

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Loxitane side effects (in more detail)

More Loxitane resources

Loxitane Side Effects (in more detail)
Loxitane Use in Pregnancy & Breastfeeding
Drug Images
Loxitane Drug Interactions
Loxitane Support Group
0 Reviews for Loxitane - Add your own review/rating

Loxitane Prescribing Information (FDA)

Loxitane MedFacts Consumer Leaflet (Wolters Kluwer)

Loxitane Concise Consumer Information (Cerner Multum)

Loxitane Monograph (AHFS DI)

Loxapine Prescribing Information (FDA)

Loxapine Professional Patient Advice (Wolters Kluwer)

Compare Loxitane with other medications

Schizophrenia

Tuesday, September 27, 2016

Apo-Oflox

Apo-Oflox may be available in the countries listed below.

Ingredient matches for Apo-Oflox

Ofloxacin

Ofloxacin is reported as an ingredient of Apo-Oflox in the following countries:

Canada

Guyana

International Drug Name Search

Climodiène

Climodiène may be available in the countries listed below.

Ingredient matches for Climodiène

Dienogest

Dienogest is reported as an ingredient of Climodiène in the following countries:

France

Estradiol

Estradiol 17ß-valerate (a derivative of Estradiol) is reported as an ingredient of Climodiène in the following countries:

France

International Drug Name Search

Colestricon

Colestricon may be available in the countries listed below.

Ingredient matches for Colestricon

Simvastatin

Simvastatin is reported as an ingredient of Colestricon in the following countries:

Philippines

International Drug Name Search

Cefoxin

Cefoxin may be available in the countries listed below.

Ingredient matches for Cefoxin

Cefoxitin

Cefoxitin sodium salt (a derivative of Cefoxitin) is reported as an ingredient of Cefoxin in the following countries:

Thailand

International Drug Name Search

Diocto

In the US, Diocto (docusate systemic) is a member of the drug class laxatives and is used to treat Constipation.

US matches:

Diocto Liquid

Diocto Syrup

Diocto

Ingredient matches for Diocto

Docusate

Docusate Sodium is reported as an ingredient of Diocto in the following countries:

United States

International Drug Name Search

Nitrazepam Zizhu Pharm

Nitrazepam Zizhu Pharm may be available in the countries listed below.

Ingredient matches for Nitrazepam Zizhu Pharm

Nitrazepam

Nitrazepam is reported as an ingredient of Nitrazepam Zizhu Pharm in the following countries:

China

International Drug Name Search

Lamotrigine EG

Lamotrigine EG may be available in the countries listed below.

Ingredient matches for Lamotrigine EG

Lamotrigine

Lamotrigine is reported as an ingredient of Lamotrigine EG in the following countries:

Belgium

France

Luxembourg

International Drug Name Search

Flubendazol

Flubendazol may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Flubendazol

Flubendazole

Flubendazole is reported as an ingredient of Flubendazol in the following countries:

Germany

International Drug Name Search

Monday, September 26, 2016

Lozitan

Lozitan may be available in the countries listed below.

Ingredient matches for Lozitan

Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Lozitan in the following countries:

India

International Drug Name Search

Colircusi Atropine

Colircusi Atropine may be available in the countries listed below.

Ingredient matches for Colircusi Atropine

Atropine

Atropine sulfate (a derivative of Atropine) is reported as an ingredient of Colircusi Atropine in the following countries:

Taiwan

International Drug Name Search

piperacillin and tazobactam

Generic Name: piperacillin and tazobactam (pi PER a sil in and tay zoe BAK tam)

Brand Names: Zosyn

What is piperacillin and tazobactam?

Piperacillin is a penicillin antibiotic that fights bacteria in the body.

Tazobactam is an antibiotic similar to a penicillin that fights bacteria in the body.

The combination of piperacillin and tazobactam is used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach infections, skin infections, and pneumonia.

This medication is sometimes given together with other antibiotics.

Piperacillin and tazobactam may also be used for purposes not listed in this medication guide.

What is the most important information I should know about piperacillin and tazobactam?

You should not use this medication if you are allergic to piperacillin and tazobactam or to any other penicillin antibiotic, such as amoxicillin (Amoxil, Augmentin, Dispermox, Moxatag), ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), ticarcillin (Timentin), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen), and others.

Before using piperacillin and tazobactam tell your doctor if you have kidney disease, a bleeding or blood clotting disorder, low levels of potassium in your blood, cystic fibrosis, a history of allergies, if you are on a low-salt diet, or if you are allergic to a cephalosporin antibiotic such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Piperacillin and tazobactam will not treat a viral infection such as the common cold or flu.

Piperacillin and tazobactam may cause bleeding, especially in people with kidney disease or using certain medicines. Tell your doctor if you are using any medication to prevent blood clots such as alteplase (Activase), bivalirudin (Angiomax), clopidogrel (Plavix), dabigatran (Pradaxa), dipyridamole (Persantine, Aggrenox), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin, tenecteplase (TNKase), ticlopidine (Ticlid), tinzaparin (Innohep), warfarin (Coumadin, Jantoven), and others.

What should I discuss with my healthcare provider before using piperacillin and tazobactam?

You should not use this medication if you are allergic to piperacillin and tazobactam or to any other penicillin antibiotic, such as:

amoxicillin (Amoxil, Augmentin, Dispermox, Moxatag);

ampicillin (Principen, Unasyn);

dicloxacillin (Dycill, Dynapen);

oxacillin (Bactocill);

ticarcillin (Timentin); or

penicillin (Bicillin L-A, PC Pen VK, Pfizerpen), and others.

To make sure you can safely use piperacillin and tazobactam, tell your doctor if you have any of these other conditions:

kidney disease (or if you are on dialysis);

a bleeding or blood clotting disorder;

an electrolyte imbalance such as low levels of potassium in your blood;

cystic fibrosis;

a history of any type of allergy;

if you are on a low-salt diet; or

if you are allergic to a cephalosporin antibiotic such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others.

FDA pregnancy category B. Piperacillin and tazobactam is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Piperacillin and tazobactam may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use piperacillin and tazobactam?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Piperacillin and tazobactam is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Piperacillin and tazobactam must be given slowly, and the IV infusion can take at least 30 minutes to complete.

Piperacillin and tazobactam must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

Prepare your dose in a syringe, IV bag, or infusion pump only when you are ready to give yourself an injection. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.

Piperacillin and tazobactam is usually given for 7 to 10 days, depending on the infection being treated. Follow your doctor's instructions.

If you use this medication long-term, your blood will need to be tested often. Visit your doctor regularly.

Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using piperacillin and tazobactam.

Store unmixed medicine and the liquid diluent at cool room temperature.

Medicine mixed in an IV bag must be used within 24 hours if you keep it at room temperature.

Mixed medicine in an infusion pump must be used within 12 hours if you keep it at room temperature.

Mixed medication in an IV bag can also be stored in the refrigerator for up to 7 days. Do not freeze. Throw away any unused mixture that has not been used within that time.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe anxiety, agitation, feeling restless or nervous, or seizure (convulsions).

What should I avoid while using piperacillin and tazobactam?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Piperacillin and tazobactam side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

diarrhea that is watery or bloody;

pale or yellowed skin, dark colored urine, fever, confusion or weakness;

feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

dry mouth, increased thirst, confusion, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips; or

seizure (convulsions).

Less serious side effects may include:

nausea, vomiting, stomach pain or upset;

constipation, mild diarrhea;

headache, dizziness, agitation;

runny nose;

anxiety, sleep problems (insomnia);

skin rash or itching;

pain, swelling, or other irritation where the injection was given; or

vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Piperacillin and tazobactam Dosing Information

Usual Adult Dose for Aspiration Pneumonia:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: Parenteral therapy should be continued until the patient's clinical condition stabilizes and fever subsides. Oral antibiotic therapy may then be substituted according to microbiology sensitivity data. Therapy of documented anaerobic pleuropulmonary infections should be continued until the infiltrate is cleared, or a residual scar forms, sometimes for as long as 2 to 4 months.

Usual Adult Dose for Bacteremia:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for approximately 14 days, depending on the nature and severity of the infection; once the patient is stable and able to tolerate oral medications, oral antibiotic therapy may be substituted according to microbiology sensitivity data

In severe infections, piperacillin trough levels (drawn immediately before the 4th or 5th dose) may be helpful. Serum piperacillin trough levels greater than 16 mcg/mL have been associated with improved efficacy.

Usual Adult Dose for Deep Neck Infection:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for approximately 2 to 3 weeks, depending on the nature and severity of the infection; once the patient is stable and able to tolerate oral medications, oral antibiotic therapy may be substituted according to microbiology sensitivity data

Usual Adult Dose for Endometritis:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: Parenteral therapy should be continued for at least 24 hours after the patient has remained afebrile, pain-free, and the leukocyte count has normalized. Doxycycline therapy for 14 days is recommended if concurrent chlamydial infection is present in late postpartum patients (breast-feeding should be discontinued).

Usual Adult Dose for Febrile Neutropenia:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: Therapy should be continued for about 14 days, or until more specific therapy may be substituted for a proven infection, or until the patient is afebrile for 24 hours after the absolute neutrophil count is greater than 500/mm3. The total duration of therapy depends on the nature and severity of the infection. Once the patient is stable and able to tolerate oral medications, oral antibiotic therapy may be substituted according to microbiology sensitivity data.

In severe infections, piperacillin trough levels (drawn immediately before the 4th or 5th dose) may be helpful. Serum piperacillin trough levels greater than 16 mcg/ml have been associated with improved efficacy.

Usual Adult Dose for Intraabdominal Infection:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for 7 to 10 days, depending on the nature and severity of the infection; once the patient is stable and able to tolerate oral medications, oral antibiotic therapy may be substituted according to microbiology sensitivity data

In severe infections, piperacillin trough levels (drawn immediately before the 4th or 5th dose) may be helpful. Serum piperacillin trough levels greater than 16 mcg/mL have been associated with improved efficacy.

Usual Adult Dose for Joint Infection:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: Therapy should be continued for approximately 3 to 4 weeks, depending on the nature and severity of the infection. Longer therapy, 6 weeks or more, may be required for prosthetic joint infections. In addition, removal of the involved prosthesis is usually required.

Usual Adult Dose for Nosocomial Pneumonia:

Moderate to severe: 4.5 g IV every 6 hours
Duration: for 7 to 14 days, depending on the nature and severity of the infection

Initial empiric treatment with broad-spectrum coverage according to the hospital's and/or ICU's antibiogram is recommended if multidrug-resistant organisms are suspected.

If the causative organism is not Pseudomonas aeruginosa, the duration of treatment should be as short as clinically possible (e.g., as little as 7 days) to reduce the risk of superinfections with resistant organisms.

Usual Adult Dose for Osteomyelitis:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: Therapy should be continued for approximately 4 to 6 weeks, depending on the nature and severity of the infection. Chronic osteomyelitis may require additional oral antibiotic therapy, possibly for up to 6 months. Surgical debridement of devitalized bone is critical to the management of osteomyelitis.

Usual Adult Dose for Pelvic Inflammatory Disease:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for 7 to 10 days, depending on the nature and severity of the infection

If the patient is not pregnant, oral doxycycline therapy for 14 days should be considered to treat possible concurrent chlamydial infection. The patient's sexual partner(s) should also be evaluated.

Usual Adult Dose for Peritonitis:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for 7 to 10 days, depending on the nature and severity of the infection

Usual Adult Dose for Skin or Soft Tissue Infection:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for 7 to 10 days, depending on the nature and severity of the infection

Usual Adult Dose for Pneumonia:

Moderate community-acquired pneumonia: 3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for 7 to 10 days, depending on the nature and severity of the infection

Usual Adult Dose for Pyelonephritis:

Usual Adult Dose for Urinary Tract Infection:

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used
Duration: for approximately 7 to 10 days, depending on the nature and severity of the infection; once the patient is stable and able to tolerate oral medications, oral antibiotic therapy may be substituted according to microbiology sensitivity data

Usual Pediatric Dose for Appendectomy:

2 to 9 months: 80 mg-10 mg/kg piperacillin-tazobactam IV every 8 hours
9 months or older (less than 40 kg): 100 mg-12.5 mg/kg piperacillin-tazobactam IV every 8 hours

Pediatric patients weighing over 40 kg with normal renal function should receive adult dose.

Usual Pediatric Dose for Peritonitis:

What other drugs will affect piperacillin and tazobactam?

Piperacillin and tazobactam may cause bleeding, especially in people with kidney disease or using certain medicines. Tell your doctor if you are using any medication to prevent blood clots, such as:

abciximab (ReoPro);

alteplase (Activase);

anagrelide (Agrylin);

argatroban (Acova);

bivalirudin (Angiomax);

cilostazol (Pletal);

clopidogrel (Plavix);

dipyridamole (Persantine);

dabigatran (Pradaxa);

dalteparin (Fragmin);

dipyridamole (Persantine, Aggrenox);

enoxaparin (Lovenox);

eptifibatide (Integrelin);

fondaparinux (Arixtra);

heparin;

lepirudin (Refludan);

prasugrel (Effient);

tenecteplase (TNKase);

ticlopidine (Ticlid);

tinzaparin (Innohep);

tirofiban (Aggrastat);

urokinase (Abbokinase); or

warfarin (Coumadin, Jantoven).

Tell your doctor about all other medicines you use, especially:

probenecid (Benemid); or

another antibiotic such as kanamycin (Kantrex), neomycin (Mycifradin, Neo Fradin, Neo Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).

This list is not complete and other drugs may interact with piperacillin and tazobactam. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More piperacillin and tazobactam resources

Piperacillin and tazobactam Side Effects (in more detail)
Piperacillin and tazobactam Dosage
Piperacillin and tazobactam Use in Pregnancy & Breastfeeding
Piperacillin and tazobactam Drug Interactions
Piperacillin and tazobactam Support Group
1 Review for Piperacillin and tazobactam - Add your own review/rating

Compare piperacillin and tazobactam with other medications

Appendectomy
Aspiration Pneumonia
Bacteremia
Bone infection
Deep Neck Infection
Endometritis
Febrile Neutropenia
Intraabdominal Infection
Joint Infection
Kidney Infections
Nosocomial Pneumonia
Pelvic Inflammatory Disease
Peritonitis
Pneumonia
Skin Infection
Urinary Tract Infection

Where can I get more information?

Your doctor or pharmacist can provide more information about piperacillin and tazobactam.

See also: piperacillin and tazobactam side effects (in more detail)

Capto comp-1A Pharma

Capto comp-1A Pharma may be available in the countries listed below.

Ingredient matches for Capto comp-1A Pharma

Captopril

Captopril is reported as an ingredient of Capto comp-1A Pharma in the following countries:

Germany

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Capto comp-1A Pharma in the following countries:

Germany

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Thursday, September 29, 2016

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Wednesday, September 28, 2016

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Tuesday, September 27, 2016

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Monday, September 26, 2016

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