Clipto

Clipto may be available in the countries listed below.

Ingredient matches for Clipto

Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Clipto in the following countries:

• Spain

International Drug Name Search

Porabutin

Porabutin may be available in the countries listed below.

Ingredient matches for Porabutin

Oxybutynin

Oxybutynin hydrochloride (a derivative of Oxybutynin) is reported as an ingredient of Porabutin in the following countries:

• Japan

International Drug Name Search

Lanicor

Lanicor may be available in the countries listed below.

Ingredient matches for Lanicor

Digoxin

Digoxin is reported as an ingredient of Lanicor in the following countries:

• Argentina


• Botswana


• Croatia (Hrvatska)


• Czech Republic


• Ecuador


• Germany


• Ghana


• Kenya


• Luxembourg


• Malawi


• Namibia


• Nigeria


• Sudan


• Tanzania


• Uganda


• Venezuela


• Zambia


• Zimbabwe

International Drug Name Search

Lanoxin Elixir

Pronunciation: di-JOX-in
Generic Name: Digoxin
Brand Name: Lanoxin

Lanoxin Elixir is used for:

Treating heart failure or slowing the heart rate in patients with chronic atrial fibrillation, a type of abnormal heart rhythm. It may also be used for other conditions as determined by your doctor.

Lanoxin Elixir is a digitalis glycoside. It works by increasing the force of contraction of the heart and slowing heart rate.

Do NOT use Lanoxin Elixir if:

• you are allergic to any ingredient in Lanoxin Elixir


• you are taking sucralfate


• you have certain types of heart rhythm problems, such as ventricular fibrillation

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lanoxin Elixir:

Some medical conditions may interact with Lanoxin Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have severe heart failure or other heart problems (eg, inflammation, heart block, cor pulmonale, cardiomyopathy, amyloid heart disease ), extra heart beats (premature ventricular contractions [PVCs]), other types of abnormal heart rhythm, heart problems due to low thiamine (eg, beriberi heart disease), Wolff-Parkinson-White syndrome, heart blood vessel problems, or fainting due to a heart problem


• if you have severe kidney, liver, or lung problems, or thyroid problems


• if you have low blood levels of calcium, magnesium, or potassium, or high blood levels of potassium or calcium


• if you have had a recent heart attack

Some MEDICINES MAY INTERACT with Lanoxin Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alprazolam, amiodarone, amphotericin B, anticholinergics (eg, propantheline), beta-blockers (eg, propranolol, carvedilol), bupivacaine, calcium, cyclosporine, diltiazem, diphenoxylate, diuretics (eg, furosemide, hydrochlorothiazide), indomethacin, itraconazole, macrolides (eg, erythromycin), propafenone, quinidine, quinine, spironolactone, stimulants (eg, amphetamine), succinylcholine, sympathomimetics (eg, albuterol, pseudoephedrine), tetracyclines (eg, doxycycline), thioamines (eg, methimazole), or verapamil because they may increase the risk of Lanoxin Elixir's side effects, especially on the heart


• Acarbose, certain anticancer medicines, cholestyramine, colestipol, kaolin-pectin, metoclopramide, penicillamine, rifampin, sulfasalazine, or thyroid hormones (eg, levothyroxine) because they may decrease Lanoxin Elixir's effectiveness


• Oral aminoglycosides (eg, neomycin) because the actions and side effects of Lanoxin Elixir may be increased or decreased


• Spironolactone because it may interfere with certain lab tests for digoxin blood levels and give incorrect readings

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lanoxin Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lanoxin Elixir:

Use Lanoxin Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lanoxin Elixir by mouth. Do not take it within 1 hour of food high in fiber.


• Do not take antacids containing aluminum or magnesium, cholestyramine, or colestipol within 2 to 4 hours of taking Lanoxin Elixir.


• Use the dropper that comes with Lanoxin Elixir to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Lanoxin Elixir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lanoxin Elixir.

Important safety information:

• Lanoxin Elixir may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Lanoxin Elixir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Tell your doctor or dentist that you take Lanoxin Elixir before you receive any medical or dental care, emergency care, or surgery.


• Lanoxin Elixir may interfere with certain lab tests, including an electrocardiogram (ECG). Be sure your doctor and lab personnel know you are using Lanoxin Elixir.


• Lab tests, including ECG, electrolytes, kidney function, and blood digoxin levels, may be performed while you use Lanoxin Elixir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Lanoxin Elixir with caution in the ELDERLY; they may be more sensitive to its effects.


• Use Lanoxin Elixir with extreme caution in NEWBORN INFANTS, especially those who are premature or immature; they may be more sensitive to its effects.


• Poisoning may occur in children who accidently swallow Lanoxin Elixir or receive too much medicine. In case of an overdose, call a doctor or poison control center right away.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lanoxin Elixir while you are pregnant. Lanoxin Elixir is found in breast milk. If you are or will be breast-feeding while you are taking Lanoxin Elixir, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lanoxin Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, yellow vision, or other vision changes; confusion; fast, slow, or irregular heartbeat; hallucinations; mood or mental changes (eg, depression); severe or persistent nausea, vomiting, or stomach pain; unusual bruising or bleeding; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lanoxin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include very fast, very slow, or irregular heartbeat.

Proper storage of Lanoxin Elixir:

Store Lanoxin Elixir at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lanoxin Elixir out of the reach of children and away from pets.

General information:

• If you have any questions about Lanoxin Elixir, please talk with your doctor, pharmacist, or other health care provider.


• Lanoxin Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lanoxin Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lanoxin resources

• Lanoxin Side Effects (in more detail)
• Lanoxin Use in Pregnancy & Breastfeeding
• Drug Images
• Lanoxin Drug Interactions
• Lanoxin Support Group
• 0 Reviews for Lanoxin - Add your own review/rating

Compare Lanoxin with other medications

• Atrial Fibrillation
• Heart Failure

Prefaxine

Prefaxine may be available in the countries listed below.

Ingredient matches for Prefaxine

Venlafaxine

Venlafaxine hydrochloride (a derivative of Venlafaxine) is reported as an ingredient of Prefaxine in the following countries:

• Slovakia

International Drug Name Search

Clonazone

Clonazone may be available in the countries listed below.

Ingredient matches for Clonazone

Tosylchloramide Sodium

Tosylchloramide Sodium is reported as an ingredient of Clonazone in the following countries:

• Belgium

International Drug Name Search

Pulmicort Nasal Turbuhaler

Pulmicort Nasal Turbuhaler may be available in the countries listed below.

Ingredient matches for Pulmicort Nasal Turbuhaler

Budesonide

Budesonide is reported as an ingredient of Pulmicort Nasal Turbuhaler in the following countries:

• Chile

International Drug Name Search

Saphris

Generic Name: asenapine (Sublingual route)

a-SEN-a-peen

Sublingual route(Tablet)

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Asenapine is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

• Saphris

Available Dosage Forms:

• Tablet

Uses For Saphris

Asenapine is used to treat symptoms of psychotic (mental) disorders, such as schizophrenia, mania, or bipolar disorder. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.

Before Using Saphris

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of asenapine in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of asenapine in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Cisapride


• Dronedarone


• Mesoridazine


• Metoclopramide


• Pimozide


• Sparfloxacin

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Ajmaline


• Alfuzosin


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Apomorphine


• Arsenic Trioxide


• Astemizole


• Azimilide


• Azithromycin


• Bretylium


• Chloroquine


• Chlorpromazine


• Ciprofloxacin


• Citalopram


• Clarithromycin


• Clomipramine


• Clozapine


• Crizotinib


• Dasatinib


• Desipramine


• Disopyramide


• Dofetilide


• Dolasetron


• Droperidol


• Erythromycin


• Flecainide


• Fluconazole


• Gatifloxacin


• Gemifloxacin


• Granisetron


• Halofantrine


• Haloperidol


• Hydroquinidine


• Ibutilide


• Iloperidone


• Imipramine


• Lapatinib


• Levofloxacin


• Lopinavir


• Lumefantrine


• Mefloquine


• Methadone


• Moxifloxacin


• Nilotinib


• Norfloxacin


• Nortriptyline


• Octreotide


• Ofloxacin


• Ondansetron


• Paliperidone


• Pazopanib


• Perflutren Lipid Microsphere


• Pirmenol


• Posaconazole


• Prajmaline


• Procainamide


• Prochlorperazine


• Promethazine


• Propafenone


• Protriptyline


• Quetiapine


• Quinidine


• Quinine


• Ranolazine


• Risperidone


• Salmeterol


• Saquinavir


• Sematilide


• Sertindole


• Sodium Phosphate


• Sodium Phosphate, Dibasic


• Sodium Phosphate, Monobasic


• Solifenacin


• Sorafenib


• Sotalol


• Sultopride


• Sunitinib


• Tedisamil


• Telavancin


• Telithromycin


• Terfenadine


• Tetrabenazine


• Thioridazine


• Toremifene


• Trazodone


• Trifluoperazine


• Trimipramine


• Vandetanib


• Vardenafil


• Vemurafenib


• Voriconazole


• Ziprasidone


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Fluvoxamine


• Paroxetine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood vessel or circulation problems or


• Dehydration or


• Heart attack, history of or


• Heart disease or


• Heart failure or


• Heart rhythm problems (e.g., arrhythmia, QT prolongation) or


• Hypotension (low blood pressure) or


• Hypovolemia (low amount of blood) or


• Stroke, history of—May cause side effects to become worse.

• Bradycardia (slow heartbeat), history of or


• Heart rhythm problem (e.g., congenital long QT syndrome) or


• Hypokalemia (low potassium in the blood) or


• Hypomagnesemia (low magnesium in the blood)—May increase risk for more serious side effects.

• Diabetes or


• Hyperglycemia (high blood sugar)—This medicine may raise your blood sugar levels.

• Hyperprolactinemia (high prolactin in the blood) or


• Neuroleptic malignant syndrome (NMS), history of or


• Seizures, history of or


• Trouble with swallowing—Use with caution. May make these conditions worse.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Saphris

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

To use the sublingual tablet:

• Make sure your hands are dry before you handle the tablet.


• Do not open the blister pack that contains the tablet until you are ready to take it.


• Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil.


• Place the tablet under your tongue. It should melt quickly.


• Do not crush, chew, or swallow the tablet.


• Do not eat or drink anything for at least 10 minutes after using this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (sublingual tablets):
  
  • For bipolar disorder:
    
    • Adults—At first, 10 milligrams (mg) two times a day. Your doctor may adjust your dose as needed.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For schizophrenia:
    
    • Adults—At first, 5 milligrams (mg) two times a day. Your doctor may increase your dose as needed.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Saphris

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.

Stop using this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while using this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

For diabetic patients: This medicine may affect your blood sugar levels. Check with your doctor right away if you have increased thirst or increased urination. If you notice a change in the results of your urine or blood sugar tests, or if you have any questions, check with your doctor.

This medicine may increase your weight. Your doctor may need to check your weight on a regular basis while you are using this medicine. Talk to your doctor about ways to prevent weight gain.

This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; dizziness or lightheadedness; trouble breathing; trouble swallowing; or any swelling of your hands, face, tongue, or throat while you are using this medicine.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position suddenly. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

Asenapine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

This medicine can cause changes in the heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects. Contact your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.

This medicine may cause dizziness, drowsiness, trouble with thinking, or trouble with controlling body movements. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that requires you to be alert, well-coordinated, or able to think well.

This medicine might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might vomit or have an upset stomach. Do not get too hot while you are exercising. Avoid places that are very hot. Call your doctor if you are too hot and cannot cool down.

Asenapine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies. If you or your caregiver notice any of these side effects, tell your doctor right away.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicines including other narcotics; medicine for seizures (e.g., barbiturates); muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Saphris Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Abnormal or decreased touch sensation


• inability to move the eyes


• inability to sit still


• increase in body movements


• increased blinking or spasms of the eyelid


• lip smacking or puckering


• need to keep moving


• puffing of the cheeks


• rapid or worm-like movements of the tongue


• restlessness


• shakiness in the legs, arms, hands, or feet


• sticking out of tongue


• trembling or shaking of the hands or feet


• trouble with breathing, speaking, or swallowing


• twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs


• uncontrolled chewing movements


• uncontrolled twisting movements of the neck, trunk, arms, or legs


• unusual facial expressions


• weakness of the arms and legs

Less common

• Blurred vision


• dizziness


• headache


• nervousness


• pounding in the ears


• slow or fast heartbeat

Rare

• Black, tarry stools


• bleeding gums


• blood in the urine or stools


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• changes in patterns and rhythms of speech


• coma


• confusion


• convulsions


• decreased urine output


• fast, pounding, or irregular heartbeat or pulse


• increased thirst


• muscle pain or cramps


• nausea or vomiting


• pale skin


• pinpoint red spots on the skin


• shortness of breath


• slurred speech


• swelling of the face, ankles, or hands


• troubled breathing with exertion


• unusual bleeding or bruising


• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation


• sleepiness or unusual drowsiness


• sleeplessness


• trouble sleeping


• unable to sleep


• unusually deep sleep


• unusually long duration of sleep

Less common

• Acid or sour stomach


• belching


• depression


• difficulty with moving


• dry mouth


• fear or nervousness


• heartburn


• increased appetite


• increased watering of the mouth


• increased weight


• indigestion


• irritability


• muscle pain or stiffness


• pain in the arms or legs


• pain in the joints


• stomach discomfort, upset, or pain


• toothache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Saphris side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Saphris resources

• Saphris Side Effects (in more detail)
• Saphris Use in Pregnancy & Breastfeeding
• Drug Images
• Saphris Drug Interactions
• Saphris Support Group
• 84 Reviews for Saphris - Add your own review/rating

• Saphris Prescribing Information (FDA)


• Saphris Consumer Overview


• Saphris Monograph (AHFS DI)


• Saphris MedFacts Consumer Leaflet (Wolters Kluwer)


• Asenapine Professional Patient Advice (Wolters Kluwer)

Compare Saphris with other medications

• Bipolar Disorder
• Post Traumatic Stress Disorder
• Schizoaffective Disorder
• Schizophrenia

Iso-Eremfat

Iso-Eremfat may be available in the countries listed below.

Ingredient matches for Iso-Eremfat

Isoniazid

Isoniazid is reported as an ingredient of Iso-Eremfat in the following countries:

• Georgia


• Germany

Rifampicin

Rifampicin is reported as an ingredient of Iso-Eremfat in the following countries:

• Georgia


• Germany

International Drug Name Search

Pramipex

Pramipex may be available in the countries listed below.

Ingredient matches for Pramipex

Pramipexole

Pramipexole is reported as an ingredient of Pramipex in the following countries:

• India

International Drug Name Search

Impugan

Impugan may be available in the countries listed below.

Ingredient matches for Impugan

Furosemide

Furosemide is reported as an ingredient of Impugan in the following countries:

• Bahrain


• Cyprus


• Egypt


• Ethiopia


• Indonesia


• Iraq


• Jordan


• Kuwait


• Lebanon


• Libya


• Qatar


• Saudi Arabia


• Sudan


• Sweden


• United Arab Emirates


• Yemen

International Drug Name Search

Lodosyn

Pronunciation: KAR-bi-DOE-pa
Generic Name: Carbidopa
Brand Name: Lodosyn

Lodosyn is used for:

Treating symptoms associated with Parkinson disease and parkinsonism-like symptoms caused by other conditions. It is used in combination with another medicine called levodopa. It may also be used for other conditions as determined by your doctor.

Lodosyn is an antiparkinson agent. It works by helping levodopa to reach the brain.

Do NOT use Lodosyn if:

• you are allergic to any ingredient in Lodosyn


• you have narrow-angle glaucoma, undiagnosed skin growths, skin cancer, or a history of skin cancer


• you have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lodosyn:

Some medical conditions may interact with Lodosyn. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have an irregular heartbeat, heart disease, ulcer, seizures, blood pressure problems, asthma, lung problems, liver or kidney problems, blood or hormone problems, stomach or intestinal bleeding, glaucoma, or a history of heart attack, mental or mood problems, or suicidal thoughts or attempts

Some MEDICINES MAY INTERACT with Lodosyn. Tell your health care provider if you are taking any other medicines, especially any of the following:

• MAOIs (eg, phenelzine) because the risk of severe high blood pressure may be increased


• Tricyclic antidepressants (eg, amitriptyline) because the risk of high blood pressure or unusual muscle movements may be increased


• Metoclopramide because side effects may occur


• Blood pressure medicines or selegiline because the risk of severe dizziness on standing may be increased


• Butyrophenones, (eg, haloperidol), isoniazid, papaverine, phenothiazines (eg, chlorpromazine), or risperidone because they may decrease Lodosyn's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lodosyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lodosyn:

Use Lodosyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lodosyn by mouth on an empty stomach at least 1 hour before or 2 hours after eating.


• Carefully follow the dosing schedule given to you by your health care provider. It may take several weeks to a few months to notice benefit from use because the dose is carefully adjusted over time.


• If you are also taking iron salts (eg, ferrous sulfate), do not take them within 2 hours before or 2 hours after taking Lodosyn. Check with your doctor if you have questions


• Take Lodosyn on a regular schedule to get the most benefit from it. Taking Lodosyn at the same times each day will help you to remember to take it.


• Continue to take Lodosyn even if you feel well. Do not miss any doses.


• If you have been taking levodopa, do not start taking Lodosyn until at least 12 hours after your final dose of levodopa.


• If you miss a dose of Lodosyn, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lodosyn.

Important safety information:

• Lodosyn may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Lodosyn with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Lodosyn; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Lodosyn may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Tell your doctor or dentist that you take Lodosyn before you receive any medical or dental care, emergency care, or surgery.


• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Lodosyn. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.


• Diabetes patients - Lodosyn may cause the results of some tests for urine glucose or urine ketones to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.


• Do not suddenly stop taking Lodosyn. Some conditions may become worse when Lodosyn is suddenly stopped. Your dose may need to be slowly lowered by your doctor to avoid side effects.


• Gradually increase physical activity as your symptoms improve.


• A dark color (red, brown, or black) may appear in your saliva, urine, or sweat after taking Lodosyn. This is not harmful.


• The effects of Lodosyn might start to wear off between doses. Talk with your doctor if Lodosyn stops working well or if your condition worsens.


• Lodosyn may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Lodosyn


• Lab tests, including complete blood cell counts and liver function tests, may be performed while you use Lodosyn. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Lodosyn with caution in ELDERLY patients; they may be more sensitive to its effects.


• Lodosyn should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lodosyn while you are pregnant. It is not known if Lodosyn is found in breast milk. If you are or will be breast-feeding while you use Lodosyn, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lodosyn:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Confusion; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; taste changes; trouble sleeping; upset stomach; urinary tract infection; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in vomit; chest pain; confusion; depression; fast or irregular heartbeat; fever; hallucinations; increased sweating; mental or mood changes; muscle pain or unusual stiffness; severe abdominal pain; severe lightheadedness or fainting; sore throat; thoughts of suicide; unusual bruising or bleeding; unusual or painful movements or spasms of the face, eyelids, mouth, tongue, arms, hands, or legs; vision changes (blurred/double vision); yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lodosyn side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lodosyn:

Store Lodosyn at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lodosyn out of the reach of children and away from pets.

General information:

• If you have any questions about Lodosyn, please talk with your doctor, pharmacist, or other health care provider.


• Lodosyn is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lodosyn. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lodosyn resources

• Lodosyn Side Effects (in more detail)
• Lodosyn Use in Pregnancy & Breastfeeding
• Drug Images
• Lodosyn Drug Interactions
• Lodosyn Support Group
• 0 Reviews for Lodosyn - Add your own review/rating

• Lodosyn Prescribing Information (FDA)


• Lodosyn Concise Consumer Information (Cerner Multum)


• Lodosyn Monograph (AHFS DI)


• Carbidopa Professional Patient Advice (Wolters Kluwer)

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Calcio-cit simple

Calcio-cit simple may be available in the countries listed below.

Ingredient matches for Calcio-cit simple

Calcium Citrate

Calcium Citrate is reported as an ingredient of Calcio-cit simple in the following countries:

• Argentina

International Drug Name Search

Loxitane

Generic Name: loxapine (Oral route)

LOX-a-peen

Oral route(Capsule)

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared with placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Loxapine is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

• Loxitane

Available Dosage Forms:

• Tablet


• Capsule


• Solution

Therapeutic Class: Antipsychotic

Chemical Class: Dibenzoxazepine

Uses For Loxitane

Loxapine is used to treat a mental condition called schizophrenia.

This medicine is available only with your doctor's prescription.

Before Using Loxitane

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of loxapine in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of loxapine in geriatric patients. However, elderly patients (especially females) are more likely to have tardive dyskinesia (a movement disorder), which may require caution in patients receiving loxapine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Metoclopramide

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Hydromorphone


• Lithium


• Milnacipran


• Tramadol


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Betel Nut


• Carbamazepine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Brain tumor or


• Intestinal blockage—Loxapine may interfere with the diagnosis of these conditions.

• Breast cancer, prolactin-dependent or


• Difficult urination or


• Glaucoma or


• Heart or blood vessel disease or


• Neuroleptic malignant syndrome (NMS), history of or


• Seizures, history of or


• Urinary retention—Use with caution. May make these conditions worse.

• Coma or


• Depression, severe and caused by medicines—Should not be used in patients with these conditions.

Proper Use of Loxitane

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For schizophrenia:
  
  • For oral dosage form (capsules):
    
    • Adults—At first, 20 to 50 milligrams (mg) per day, divided and given in two to four doses per day. Your doctor may increase your dose if needed. However, the dose is usually not more than 250 mg per day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Loxitane

It is very important that your doctor check your progress at regular visits, especially during the first few months of treatment with this medicine. This will allow changes in your dose and to check for unwanted effects.

Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely. This will allow your body time to adjust and to keep your condition from becoming worse.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever or allergies; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while taking this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

Stop taking this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine may cause some people to become drowsy or less alert than they are normally, especially when the amount of medicine is increased. Even if you take this medicine at bedtime, you may feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Although it is not a problem for most patients, dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. However, if the problem continues or gets worse, check with your doctor.

Loxapine may cause dry mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Loxitane Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Difficulty with speaking or swallowing


• lip smacking or puckering


• loss of balance control


• mask-like face


• puffing of the cheeks


• rapid or fine, worm-like movements of the tongue


• restlessness or desire to keep moving


• shuffling walk


• slowed movements


• stiffness of the arms and legs


• trembling and shaking of the fingers and hands


• uncontrolled chewing movements


• uncontrolled movements of the arms or legs

Less common

• Constipation (severe)


• difficult urination


• inability to move the eyes


• muscle spasms, especially of the neck and back


• skin rash


• twisting movements of the body

Rare

• Convulsions (seizures)


• difficult or fast breathing


• fast heartbeat or irregular pulse


• fever (high)


• high or low blood pressure


• increased blinking or spasms of the eyelid


• increased sweating


• loss of bladder control


• muscle stiffness (severe)


• sore throat and fever


• uncontrolled twisting movements of neck, trunk, arms, or legs


• unusual bleeding or bruising


• unusual facial expressions or body positions


• unusual tiredness or weakness


• unusually pale skin


• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Dizziness (severe)


• drowsiness (severe)


• muscle trembling, jerking, stiffness, or uncontrolled movements (severe)


• troubled breathing (severe)


• unusual tiredness or weakness (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Blurred vision


• confusion


• dizziness, lightheadedness, or fainting


• drowsiness


• dryness of the mouth

Less common

• Constipation (mild)


• decreased sexual ability


• enlargement of breasts (males and females)


• headache


• increased sensitivity of the skin to sun


• missing menstrual periods


• nausea or vomiting


• trouble with sleeping


• unusual secretion of milk


• weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Loxitane side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Loxitane resources

• Loxitane Side Effects (in more detail)
• Loxitane Use in Pregnancy & Breastfeeding
• Drug Images
• Loxitane Drug Interactions
• Loxitane Support Group
• 0 Reviews for Loxitane - Add your own review/rating

• Loxitane Prescribing Information (FDA)


• Loxitane MedFacts Consumer Leaflet (Wolters Kluwer)


• Loxitane Concise Consumer Information (Cerner Multum)


• Loxitane Monograph (AHFS DI)


• Loxapine Prescribing Information (FDA)


• Loxapine Professional Patient Advice (Wolters Kluwer)

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